The mortality rate of neonatal sepsis was 40.74%. Chi-square test and logistic regression were used to analyze the data. A case group was obtained from medical records by a total sampling of all neonates diagnosed with neonatal sepsis in 2019, and a control group of non-neonatal sepsis cases was taken by random sampling. Methods: This was a case-control study conducted in Dr.Soetomo General Hospital. Recent data regarding preterm birth and low Apgar score as risk factors for neonatal sepsis-related death have not been reported in Indonesia. In 2018, sepsis caused approximately 15% of all neonatal deaths worldwide. Background: Neonatal sepsis is increasingly recognized as an important global health problem that challenges neonatal survival.
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